Pregabalin: A well-known prescription medication used to relieve nerve pain by calming overactive nerves.It works by decreasing the number of pain signals sent out by damaged nerves in the body.Pregabalin is commonly used for conditions like diabetic neuropathy and fibromyalgia.It helps reduce pain, tingling, and burning sensations in the nerves.

Methylcobalamin (Vitamin B12): This is the bioactive form of vitamin B12, crucial for nerve regeneration and function.It supports the repair of nerve sheaths and helps in the production of neurotransmitters.Deficiency in B12 is a common cause of peripheral neuropathy symptoms.Methylcobalamin is preferred over cyanocobalamin due to better bioavailability.

Alpha-Lipoic Acid (ALA): ALA is a potent antioxidant that reduces oxidative stress in nerve tissues.It supports energy production in cells and may improve blood flow to the nerves.Studies show ALA can help reduce numbness, burning, and pain associated with neuropathy.Its dual solubility allows it to work in both water and fat tissues for comprehensive support.

Pyridoxal-5-Phosphate (Active Vitamin B6): This active form of B6 supports neurotransmitter function and nerve signal transmission.It helps regulate inflammation and contributes to amino acid metabolism.Proper B6 levels are critical for maintaining healthy nerve tissue.Excess or deficiency can impact nerve function, so balanced dosing is key.

Folate (as L-5-Methyltetrahydrofolate): This bioactive form of folate works synergistically with B12 to support methylation.It helps in DNA synthesis, red blood cell formation, and neurological functions.Unlike synthetic folic acid, this form is readily absorbed and utilized by the body.It plays a role in reducing homocysteine levels, which are linked to nerve damage.